Precision Oncology
Carisma Therapeutics to Start Phase I Trial of CAR Monocyte in HER2-Positive Cancers
The FDA cleared the firm's investigational new drug application to study its autologous cell therapy CT-0525 in patients with solid tumors overexpressing HER2.
Quest Diagnostics, Scipher Medicine Collaborate on Rheumatoid Arthritis Test
Quest will provide RNA extraction and sequencing services for Scipher's PrismRA test, a blood-based molecular test for predicting patient response to TNF inhibitors.
Autolus Seeks FDA Approval for CAR T-Cell Therapy in B-Cell Acute Lymphoblastic Leukemia
The firm's supplemental biologics license application is based on encouraging data from a Phase II trial in more than 100 patients.
The researchers hope to reproduce in a prospective clinical trial the model's 70 percent to 80 percent accuracy for predicting immunotherapy response.
FDA Grants Abeona Therapeutics Priority Review for Wound Healing Cell Therapy Application
The agency will review data submitted by the firm from two trials showing pz-cel's ability to heal wounds for those with COL7A1-mutated recessive dystrophic epidermolysis bullosa.