Keytruda
Phase III data presented at the WCLC suggests the new VEGF and PD-L1 inhibitor could prolong progression-free survival versus Merck's anti-PD-1 blockbuster.
Keytruda Sales Climb 16 Percent in Q2 as Merck Pursues New Oncology Candidates
The drugmaker updated investors on its three-pronged strategy to diversify its pipeline and not overly rely on its top-selling blockbuster checkpoint inhibitor.
Prelude Therapeutics to Study PRT3789, Keytruda in SMARCA4-Mutant Cancers
Prelude is currently evaluating PRT3789 as a monotherapy and in combination with docetaxel in a Phase I study with SMARCA4-mutated tumors.
Merck, Moderna Personalized Neoantigen Vaccine, Keytruda Combo Still Benefiting Melanoma Patients
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After three years of follow-up, mRNA-4157 plus Keytruda led to a 49 percent reduction in the risk of disease recurrence or death versus Keytruda alone.
Upfront Amtagvi-Keytruda Shows Promise in Checkpoint Inhibitor-Naive Melanoma, but Questions Remain
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Iovance's autologous TIL therapy plus Merck's PD-1 drug led to encouraging responses in a Phase II trial, but some oncologists challenged the Phase III design.