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From decoy DNA sequences to plasmapheresis, researchers are testing strategies to get around anti-AAV antibodies that hinder gene therapy response.
In Brief This Week: MeiraGTx, IASO Biotherapeutics, Integrated DNA Technologies, Volta Labs
News items for the week of May 5, 2025.
New Preclinical Testing Tools Help Researchers Tailor Treatment but Can They Fully Replace Mice?
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Makers of organoids and cell models cheered the decision and said it will bolster the development of precision medicines, while others remain skeptical.
Marengo Begins Phase Ib/II Trial of Invikafusp Alfa, Trodelvy in Certain Breast Cancers
The study will include two cohorts of breast cancer patients: triple-negative breast cancer and HR-positive, HER2-negative breast cancer.
AstraZeneca to Discuss Neoadjuvant Enhertu Regimen With Regulators Following Early Data Readout
Patients on Enhertu followed by a chemotherapy and dual anti-HER2 regimen fared better than those on standard therapy.
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