structural variant analysis
Could PD-L1/2 Structural Variants be the Next Pan-Cancer Predictive Immunotherapy Biomarker?
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The OSUCCC researchers plan to prospectively study how well patients with PD-L1/2 structural variants do on anti-PD-1 therapy and are seeking pharma partners for that effort.
Structural Variant Study Points to Pediatric Glioma Drivers, Prognostic Features
Researchers profiled structural variant patterns in 179 pediatric high-grade glioma cases, identifying SV features linked to tumor subtypes and clinical outcomes.
Multiple Myeloma Sequences Reveal Prognostic Immunoglobulin Translocation
A structural variant analysis based on genome sequences for almost 800 multiple myeloma cases suggests a IgL translocation present in nearly 10 percent of patients may inform survival.