single-cell sequencing
UMiami Researchers to Study Cell Therapy Response in Lymphoma Using WGS, Single-Cell RNA-seq
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The team has received a $1.5 million US Department of Defense grant to help launch its project on diffuse B-cell lymphoma resistance to CAR T-cell therapy.
Through an early-access program, the company is hoping to show that its platform can identify measurable residual disease in AML more accurately than current methods.
Epic Sciences Raises $43M in Series F Round
Epic will use the funds to further develop its multi-analyte DefineMBC liquid biopsy and expand into other business areas.
New Epigenomic Biomarker Could Predict CAR T-Cell Therapy Resistance in Advanced Childhood Leukemia
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At AACR, researchers described how pediatric ALL patients who don't respond to anti-CD19 CAR T-cell therapy have cancers with a unique, stem cell-like epigenome.
Molecular Clonal Tracking Method Captures Lung Cancer Treatment Response, Resistance Features
Using a single-cell sequencing and clonal fitness mapping method, researchers compared EGFR-mutant lung cancer cell responses to EGFR inhibition or targeted protein degradation.