single-cell gene expression analysis
UMiami Researchers to Study Cell Therapy Response in Lymphoma Using WGS, Single-Cell RNA-seq
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The team has received a $1.5 million US Department of Defense grant to help launch its project on diffuse B-cell lymphoma resistance to CAR T-cell therapy.
T-Cell Subpopulations in Blood May Help Predict Immune Checkpoint Immunotherapy Side Effects
Researchers searched for baseline immune cell gene expression signatures and clusters linked to immune-related adverse events on checkpoint blockade immunotherapy.
Blood Lipid Mass Spectrometry Assay May Enable Early-Stage Lung Cancer Detection
Researchers in China have come up with a machine learning- and lipidomics-based strategy for detecting lung cancer early in blood samples.
UK Researchers Show Cytotoxic T-Cell Level Predicts Melanoma Immunotherapy Response
A Science Immunology paper details how patients with more cytotoxic effector T cells in peripheral blood at baseline respond better to checkpoint inhibitors.
New Research Consortium to Standardize Single-Cell Sequencing for Cancer Drug Resistance Studies
The main goal of the Persist-Seq private-public consortium is to generate a large single-cell cancer database in order to enable research on drug resistance.