pharmacogenomics
UK's NICE Recommends Genetic Testing for Therapy Selection in Stroke Patients
Clopidogrel is less effective at preventing subsequent strokes in patients with certain variations in the CYP2C19 gene and testing could aid treatment selection.
In the PGx-ACT trial, investigators are tracking if patients unable to fully benefit from hydrocodone, tramadol, or codeine can get on the right drug with the help of genetic testing.
MSK Researchers Want to Test New Chemo Delivery Method to Bypass Toxicity in DPD-Deficient Patients
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Based on a published case report, researchers hope to launch a Phase II trial exploring hepatic arterial infusion of chemo in DPD-deficient GI cancer patients.
Polygenic Risk Score Shows Promise Predicting Beta Blocker Response in Heart Failure Patients
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Researchers from Henry Ford Health in Detroit hope to prospectively validate the pharmacogenomics PRS's ability to predict survival benefit for patients on beta blockers.
Genomadix Gets FDA 510(k) Clearance for PCR System, CYP2C19 Test
Canada's Genomadix, formerly known as Spartan Bioscience, expects to now commercialize the system and test in the US to guide therapy decisions.