immune repertoire sequencing
Breast Cancer Study Highlights Germline Genetic Influence on Tumor Subtype, Aggressiveness
Investigators saw relationships between germline epitope burdens in frequently amplified driver genes and immunoediting-related breast cancer features.
Adaptive Biotechnologies, Takeda Partner to Develop Treatments for Lymphoid Malignancies
The multiyear collaboration will use Adaptive's ClonoSeq assay to measure minimal residual disease status as an endpoint for Takeda’s clinical trials.
Immune Signatures Outperform TILs for HER2-Positive Breast Cancer Prognoses
Immune-related gene expression signatures tracked more closely with treatment response and outcomes than tumor-infiltrating lymphocytes in early-stage HER2-positive breast cancer.
Adaptive Biotech's ClonoSeq Gets Expanded Medicare Coverage For B-Cell Lymphoma
The firm's assay is the first and only test to gain coverage for this patient population, for whom ctDNA MRD assessment can help personalize treatment.
Evaxion Biotech Adopts Personalis Immune Profiling Platform for Melanoma Immunotherapy Trial
The companies will use Personalis' ImmunoID Next technology to analyze patient response to a combination of Evaxion's EVX-01 with the immunotherapy Keytruda.