variants of unknown significance
Initial findings from the country's 10-year National Precision Medicine program could yield genetic tests tailored to Asian populations within Singapore and abroad.
American Heart Association Offers Guidelines on Reporting Incidental Findings of Sequencing Tests
Any findings on "incidental variants" related to cardiovascular diseases should only be revealed to patients if they have consented to receiving the information.
Genetic Testing Challenges in Oncology: BRCA1 Variant Downgraded After Risk-Reducing Surgery
A case series in partnership with My Gene Counsel to highlight the challenges genetics professionals and oncologists are grappling with as genetic testing is increasingly used in patient care.
A recent JAMA study underscores racial disparities in genetic test access, which UPenn's Basser Center aims to address through its Black & BRCA initiative.
BRCA2 Variants of Unknown Significance Reclassified Through Functional Data Additions
Researchers reclassified 86 percent of variants initially determined to be VUS, potentially changing surveillance or treatment approaches for patients.