Microsatellite Instability Testing
The latest news on microsatellite instability testing.
EMA's CHMP Recommends Approval for First-Line Opdivo-Yervoy in Certain Colorectal Cancers
Patients with MSI-high/dMMR advanced colorectal cancers had a 79 percent lower risk of disease progression or death on Opdivo-Yervoy compared to chemo.
Marengo Therapeutics Advancing Bispecific Antibody to Phase II After Positive First-in-Human Data
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A Phase I study of invikafusp alfa presented at SITC provided the rationale to enroll patients with TMB-high, MSI-high, and virus-associated tumors in Phase II.
Ideaya, GSK Cleared to Begin Phase I Trial of Werner Helicase Inhibitor in MSI-High Tumors
The companies have plans to evaluate IDE275 as a monotherapy and combined with immunotherapy in MSI-high solid tumors.
Researchers at the ESMO Congress presented data showing better responses on dual-checkpoint blockade in the biomarker-defined subset relative to all-comers.
Imidex, Orbit Genomics Partner to Develop Lung Cancer Detection Technologies
The collaboration aims to increase early detection rates for lung cancer via improved imaging of suspected nodules and subsequent genomic testing.