evolutionary biology
TRACERx Study Characterizes Immune Relationship to Lung Tumor Evolution
With RNA sequencing and other data, researchers gauged neoantigen formation, immunoediting, and clonal evolution in non-small cell lung cancers.
Metastatic Tumors in Individual Patients Share Driver Mutations
A phylogenetic analysis that included multiple samples per patient suggests overlapping driver mutations make their way into multiple metastases in each patient.