BRCA Biomarkers
News and reporting on BRCA biomarkers.
NICE Recommends Lynparza for BRCA1/2-Mutant Breast Cancer
The institute originally began reviewing Lynparza in this setting in 2018 but ended its review due to lack of evidence.
Risk-Reducing Surgery Improves Outcomes for Young Patients With BRCA1/2-Mutant Breast Cancer
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A global study showed breast cancer patients who underwent preventive surgeries had lower mortality and cancer recurrence risks than those who didn't.
BRCA1/2 Mutations Aren't Equal: Researchers Push for Reduced Penetrance Pathogenic Variant Category
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Researchers worked with two labs to identify 16 consensus lower-risk pathogenic variants and are pushing for greater recognition of such variants.
Transgender Patients With Hereditary Cancer Risk Variants Benefit From Individualized Approach
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Doctors are using limited guidance on screening and treatment approaches for transgender patients predisposed to cancer while considering patient preferences and treatment goals.
858 Therapeutics Raises $50M in Series B Financing Round
Funds will be used to advance a Phase I trial of 858's PARG inhibitor ETX-19477 in advanced solid tumors.