University of Toronto
Gene Therapy for Ultra-Rare Genetic Condition Shows Promise in Single-Participant Clinical Trial
A Phase I clinical trial of one affected child suggests a gene replacement therapy is a safe and potentially effective treatment for spastic paraplegia type 50.
Breast Cancer Study Leads to New Susceptibility Gene, Potential Treatment Strategies
Researchers found risk variants in the DNA damage checkpoint gene ATRIP in a Polish founder population and linked the gene to breast cancer risk and HRD in other populations.
Cyclica, University of Toronto Lab Launch Joint Venture Perturba Therapeutics
Perturba will combine AI-driven drug discovery with cell-based assays to advance programs targeting EGFR and GTPases.
Large-Scale Pan-Cancer Analysis Expands Set of Alterations Disrupting Key Genes, Pathways
Members of a large, international consortium tapped into whole-genome sequences from nearly 2,700 tumors to explore coding and non-coding variants contributing to cancer.