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I-SPY 2.2 Study IDs Early Breast Cancer Patients Who Benefit From Pre-Surgery Dato-DXd, Imfinzi
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The adaptive basket trial, which matches patients to treatments based on complex biomarker signatures, could help shape future Phase III clinical trials.
Denovo Biopharma, Anova Get $11.8M Grant to Study Biomarker-Guided Gene Therapy in Glioma Patients
Denovo, Anova, and academic partners will put the funds toward studying DB107 in certain gliomas.
The center, led by Jennifer Doudna and Fyodor Urnov and funded by Danaher, is also developing CRISPR therapies for two rare immune disorders.
Researchers have flagged 99 genes related to muscle contractility related to spontaneous preterm birth, along with nine potentially therapeutic drugs that target them.
Pluvicto monotherapy recently benefitted a similar prostate cancer population in another trial, but researchers anticipate efficacy and safety advantages with the immunotherapy combination.