UCSD
Pfizer's Ibrance Shows Benefit in Rare Appendix Cancer Study but Follow-on Research a Challenge
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The efficacy seen in a small study, especially in GNAS-mutated tumors, could influence care, but the rarity of the cancer is a challenge for further investigations.
Denovo Biopharma, Anova Get $11.8M Grant to Study Biomarker-Guided Gene Therapy in Glioma Patients
Denovo, Anova, and academic partners will put the funds toward studying DB107 in certain gliomas.
Neoantigen Detection Platform Picks up T-Cell Responses to Tumor Mutations
Researchers combined tumor sequence, transcriptome, and patient immune cell response clues in their tumor-specific neoantigen detection and validation platform.
UC San Diego Launches Gene Therapy Initiative With $5M Philanthropic Gift
Investigators and clinicians at UC San Diego will research and develop ex vivo and in vivo therapies for numerous rare genetic diseases.
Biomarker Predicts Immunotherapy Benefit in Head and Neck Cancer but Commercial Path Unclear
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Somatic 9p24.1 copy number alterations predicted the degree to which HPV-negative advanced squamous head and neck cancers benefitted from Keytruda and Opdivo.