ICR
Institute of Cancer Research, Partners Hunt for Next-Generation Drugs to Overcome KRAS Resistance
ICR is working with Bellvitge Biomedical Research Institute and Vivan Therapeutics to use AI to discover and test molecules and advance promising candidates.
RB1 Alterations in Advanced Prostate Cancer Associated With Poor Outcome
Using exome or transcriptome data from more than 400 metastatic, castration-resistant prostate cancer cases, researchers identified survival-related alterations in the RB1 gene.
The group plans to use the assay for translational studies on metastasis and drug resistance initially and to develop a clinical version later on.
Prostate Cancer Study Suggests Patients With DNA Repair Mutations May Benefit From Immunotherapy
Exome sequencing on tumors from metastatic, castration-resistant prostate cancer cases responding to immunotherapy led to homologous recombination defects.
Children With Specific Brain Tumors Could Benefit From Added Bevacizumab
Researchers analyzed HERBY trial data to uncover a subgroup of patients with MAPK pathway alterations who had increased overall survival.