AMP, CAP Release Guidelines for Use of In Silico Approaches for Validating NGS Data Pipelines
Labs should not let in silico data supplant physical specimens in bioinformatic validation and should understand the limitations of such data.
If the Center for Genomic Interpretation's in silico quality assessment catches on with payors, some labs are sure to push back or propose data sharing as an alternative.
In new guidelines, an expert panel recommended IHC and PCR for certain cancer types and pointed out knowledge gaps supporting NGS in other settings.
Enhertu Benefit in HER2-Low Breast Cancer Wows at ASCO; Signals Shifting Therapy, Dx Paradigms
Oncologists at ASCO cheered data showing the drug significantly cut the risk of disease progression or death, but experts wondered how existing HER2 testing paradigms will change in response.
Lung Cancer Biomarker Testing Survey Reveals Access Gaps, Attitudes in Community, Academic Practices
The survey conducted by ACCC revealed oncologists' lack of familiarity with biomarker testing guidelines and "prescriptive" attitudes about sharing testing decisions with patients.