Drug Discovery & Development
News on drug screening, clinical trials, companion diagnostics, immunotherapy, & personalized therapies in genetics, genomics, and molecular diagnostics.
Galapagos Inks Deal With Catalent to Use New Jersey Site for Decentralized Cell Therapy Trials
The deal advances Galapagos' plan to develop a decentralized CAR T-cell therapy for non-Hodgkin lymphoma with a one-week vein-to-vein time.
Intellia Therapeutics Doses First Patient in Phase III Hereditary Angioedema Trial of CRISPR Drug
The company expects to submit a biologics license application for NTLA-2002 in 2026 and potentially launch it in the US in 2027.
In a Phase I/II trial, patients with X-linked chronic granulomatous disease will receive a treatment created using a new approach to base editing.
Neogap Therapeutics Begins Evaluating Personalized T-Cell Therapy in Advanced Colorectal Cancer
The Swedish firm has treated the first two patients in a Phase I/II trial of the autologous neoantigen-directed lymphocyte therapy.
Cartesian Therapeutics Kicking off Phase III Cell Therapy Trial in Myasthenia Gravis
The company also continues to study Descartes-08 in other autoimmune diseases and has plans for a basket trial in pediatric patients.