Drug Discovery & Development
News on drug screening, clinical trials, companion diagnostics, immunotherapy, & personalized therapies in genetics, genomics, and molecular diagnostics.
Bristol Myers Squibb Eyeing CLL, SLL as Additional Breyanzi Indications After Positive Readout
Around 18 percent of patients in a Phase I/II trial with aggressive, treatment-refractory forms of leukemia had complete responses on the CAR T-cell therapy.
Janssen Seeking European Approval for Carvykti as Earlier Refractory Multiple Myeloma Treatment
The firm submitted data from CARTITUDE-4, which showed the CAR T-cell therapy improved patients' progression-free survival compared to standard-of-care regimens.
Insilico Medicine to Begin Phase I USP1 Inhibitor Trial Following FDA IND Clearance
The firm's IND application was supported by preclinical studies showing activity of ISM3091 against BRCA-mutant and homologous repair-deficient cancers.
Oxford BioTherapeutics, Boehringer Ingelheim Extend Drug Discovery Collaboration
The firms have previously advanced two programs identified by Oxford's platform into Phase I clinical development.
ObjectiveHealth, Urology of St. Louis Launch Research Partnership
A joint clinical research center based in St. Louis will provide access to investigative therapies and diagnostic tools to improve outcomes in urologic diseases.