Pediatric Cancer
UK Nonprofits Launch Childhood Cancer Research Program to Advance Precision Medicine
Children With Cancer UK and Cancer Research UK are providing £5.5 million to advance liquid biopsy tests to match patients to drugs and advance new therapies.
Pfizer Nets Pediatric FDA Approval for CML Drug Bosulif
The FDA approved Bosulif as either first- or later-line treatment for children with Philadelphia chromosome-positive, chronic-phase chronic myelogenous leukemia.
2seventy Bio Pauses Pediatric AML Trial of CAR T-Cell Therapy After Patient Death
The firm is investigating the death of a patient who had received SC-DARIC33 at the second dose level in the first-in-human trial.
Seattle Children's Studying CAR T-Cell Therapy Targeting Four Brain Cancer Antigens at Once
The Phase I BrainChild-04 trial will enroll pediatric, teen, and young adult patients with brain or central nervous system tumors.
Lynparza, Ceralasertib Combo Trial Provides Clues on Biomarkers of Response in Pediatric Cancer
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In the tumor-agnostic study, pediatric patients with 11q loss and other alterations associated with replication stress benefited from the dual PARP-ATR inhibitor treatment.