Pediatric Cancer
Seattle Children's Studying CAR T-Cell Therapy Targeting Four Brain Cancer Antigens at Once
The Phase I BrainChild-04 trial will enroll pediatric, teen, and young adult patients with brain or central nervous system tumors.
Lynparza, Ceralasertib Combo Trial Provides Clues on Biomarkers of Response in Pediatric Cancer
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In the tumor-agnostic study, pediatric patients with 11q loss and other alterations associated with replication stress benefited from the dual PARP-ATR inhibitor treatment.
Transcriptomic Classification of Pediatric Cancers Shows Potential to Improve Clinical Diagnoses
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In a new paper, computational biologists at Toronto's Hospital for Sick Children described their atlas of childhood cancer subtypes and a corresponding search tool.
Baylor Team Aims to Identify Chemo Toxicity Biomarkers in Latino Pediatric Leukemia Patients
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The CPRIT-funded study will examine clinical and genomic data from more than 2,000 Latino patients with acute lymphoblastic leukemia treated with high-dose chemo.
Novartis Nets FDA Approval for Tafinlar-Mekinist in Pediatric Low-Grade Glioma
Regulators approved Novartis' BRAF/MEK inhibitor combo for kids whose tumors harbor BRAF V600Emutations and simultaneously approved a new liquid form of the treatment.