Lynch syndrome
Nouscom to Advance Cancer Vaccine for Lynch Syndrome Into Registrational Study
The firm says it has a path forward for a Phase II/III registration-enabling study of NOUS-209 after positive meetings with the FDA.
Transgender Patients With Hereditary Cancer Risk Variants Benefit From Individualized Approach
Premium
Doctors are using limited guidance on screening and treatment approaches for transgender patients predisposed to cancer while considering patient preferences and treatment goals.
In a trial of 23 Lynch syndrome patients, those who received the vaccine and developed neoantigen-specific T cells had a higher chance of remaining disease-free over 10 years.
Genetic Testing Challenges in Oncology: Lynch Syndrome Variant in Patient Lacking Family History
An unexpected, deleterious MSH6 variant was found in a patient seeking preimplantation genetic testing due to relatives with cancer and a familial BRCA2 variant.
Genetic Testing Challenges in Oncology: Full Family History Helps ID Lynch Syndrome Founder Variant
In a family with a known cancer variant, genetics experts are proficient in determining whether single-site testing or panel testing is more appropriate.