gastrointestinal disease
C4X Discovery to Use Genetic Signature to Predict IBD Treatment Response in Clinical Trials
The company recently discovered this gene signature in a large dataset of patients treated with a marketed a4β7 integrin antibody for ulcerative colitis.
RCSI researchers have found a set of genes that are highly expressed in ulcerative colitis patients who progress to further stages of the disease that they hope to use in a diagnostic test.
The radioligand therapy hit roadblocks with supply constraints in early 2023, but a new manufacturing facility has since helped Novartis get back on track.
Alimentiv, AcelaBio, PharmaNest Partner to Find New NASH/MASH Biomarkers
The collaboration aims to help clinical trial sponsors understand drug effects and disease biology through spatial biology-based analyses.
Merck Closes $10.8B Prometheus Biosciences Acquisition
Prometheus' lead candidate being developed for ulcerative colitis and Crohn's disease, PRA-023, will be renamed MK-7240.