chromosomal abnormalities
Genetic Testing Challenges in Oncology: Karyotype, Germline Clues in Somatic Dx Lost in Translation
Somatic testing of patient with hematologic malignancy leads to discovery of critical chromosomal and germline findings that she didn't know about.
Pan-Cancer Analyses Reveal Copy Number Signatures, Chromosomal Instability Patterns
Investigators identified up to 21 copy number signatures in cross-cancer analyses, including potential disease response markers and signatures linked to chromosomal instability features.