Brain Cancer
Biotech firms are engineering smarter, safer gene delivery systems to enhance the safety and efficacy of genetic medicines.
The firm is using single-cell, multiomics analysis to probe tumor samples from very long-term cancer survivors for keys to defeating the disease.
Denovo, Anova Begin Brain Cancer Gene Therapy Trial Involving Response Biomarker
In an earlier study, patients with biomarker-positive high-grade glioma lived longer after treatment with DB107 than biomarker-negative patients.
FDA Grants Priority Review to Chimerix for Dordaviprone in H3 K27M-Mutant Diffuse Glioma
In a Phase III trial, 28 percent of newly diagnosed patients with H3 K27M-mutant diffuse glioma responded to treatment with dordaviprone.
BrainChild Bio Pursuing Pivotal Trial of CAR T Therapy in Pediatric Brain Cancer
The firm has discussed positive Phase I results on BCB-276 with the FDA and plans to move it directly to a registrational trial by year-end.