Precision Medicine Trends
News and analysis on diagnostic technologies and applications.
Cepheid Nabs CE-IVD Mark for Molecular NPM1 Mutation Test for AML Monitoring
The test quantifies mutant NPM1 mRNA transcripts in peripheral blood specimens from patients with acute myeloid leukemia.
Real-World Study Examines Genomic Profiling Challenges for Patients With Cancers of Unknown Primary
The researchers found that more than half of patients with CUP did not have sufficient tissue to undergo genomic profiling.
Bristol Myers Squibb Eyeing CLL, SLL as Additional Breyanzi Indications After Positive Readout
Around 18 percent of patients in a Phase I/II trial with aggressive, treatment-refractory forms of leukemia had complete responses on the CAR T-cell therapy.
Janssen Seeking European Approval for Carvykti as Earlier Refractory Multiple Myeloma Treatment
The firm submitted data from CARTITUDE-4, which showed the CAR T-cell therapy improved patients' progression-free survival compared to standard-of-care regimens.
Insilico Medicine to Begin Phase I USP1 Inhibitor Trial Following FDA IND Clearance
The firm's IND application was supported by preclinical studies showing activity of ISM3091 against BRCA-mutant and homologous repair-deficient cancers.