Cardiovascular Disease
News on molecular diagnostics, pharmacogenomics tests for coronary artery disease, congenital heart defects, and more.
UK's NICE Recommends Genetic Testing for Therapy Selection in Stroke Patients
Clopidogrel is less effective at preventing subsequent strokes in patients with certain variations in the CYP2C19 gene and testing could aid treatment selection.
Rocket Pharmaceuticals to Start Phase I Trial for Arrhythmogenic Cardiomyopathy Gene Therapy
The FDA has cleared the company's investigational new drug application for RP-A601, a gene therapy targeting mutations in the PKP2 gene.
Tenaya Therapeutics on Track to Start Hypertrophic Cardiomyopathy Gene Therapy Trial in Q3
The firm is developing TN-201, which also has fast-track status from the FDA, for symptomatic adults with MYBPC3-mutated nonobstructive HCM.
Silence Therapeutics Finishes Enrolling Zerlasiran Trial of Patients at Cardiovascular Disease Risk
The ALPACAR-360 study involves 160 individuals with high Lp(a) levels who will receive zerlasiran, a drug that targets Lp(a) mRNA in the liver.
Silence Therapeutics Finishes Enrolling Zerlasiran Trial of Patients at Cardiovascular Disease Risk
The ALPACAR-360 study involves 160 individuals with high Lp(a) levels who will receive zerlasiran, a drug that targets Lp(a) mRNA in the liver.