phase I clinical study
FDA Clears Aro Biotherapeutics' siRNA Drug IND for Late-Onset Pompe Disease
The company has already kicked off an open-label Phase I trial of ABX1100 in Canada following positive results from a study of healthy volunteers.
UniQure Testing Higher Gene Therapy Dose in Phase I/II Fabry Disease Trial
The firm will begin testing a second dose cohort with AMT-191 after receiving a positive recommendation from a data monitoring committee.
UniQure Testing Higher Gene Therapy Dose in Phase I/II SOD1-ALS Trial
With permission from a data safety monitoring committee, the firm will begin treating a second cohort with AMT-162 in the EPISOD1 trial in early 2025.
Innate Pharma Begins Phase I Trial of IPH4502 in Nectin-4-Expressing Solid Tumors
The trial will include patients with non-small cell lung, breast, ovarian, gastric, esophageal, and colorectal cancers.
BlossomHill Therapeutics Begins Trial of BH-30643 in EGFR-, HER2-Mutant NSCLC
BH-30643 is an OMNI-EGFR inhibitor that targets classical, atypical, and compound EGFR mutations and acquired resistance mutations in HER2.