NCCN Publishes First Guidelines for Pediatric Brain Cancer, Recommends Broad NGS Profiling
The guidelines recognize the importance of molecular profiling in diagnosing, treating, and identifying clinical trial opportunities for children with high-grade gliomas.
ESMO Releases Guidelines for Liquid Biopsy Testing in Cancer Patients
While the society endorsed widely used ctDNA genotyping to guide therapy in advanced cases, it rated most other emerging applications as unproven.
ESMO Advances Biomarker Framework to Guide Cancer Therapy De-Intensification, Decision-Making
The framework, which ranks de-intensification biomarkers by evidence tiers, could give oncologists, patients, regulators, and payors a common system to guide their use.
Guidelines Update Supports Use of Genomic Tests in Early Prostate Cancer Management
Although authors cautioned against routine testing, they wrote that clinicians may consider genomic testing in cases where it might change their clinical decisions.
NCCN, SNMMI Update Guidelines to Expand PET Imaging Agents for Pluvicto Eligibility
The organizations said fluorine-18-based PET imaging can be used to screen mCRPC patients for Pluvicto in addition to the gallium-68-based agent noted on FDA labeling.