Researchers have flagged 99 genes related to muscle contractility related to spontaneous preterm birth, along with nine potentially therapeutic drugs that target them.
Cardiovascular risk scores from a common tool and one with a PRS added correlated well with each other, with the added PRS impacting some care decisions.
A novel computational approach to molecular profiling was used to analyze multiple biomarker types together, resulting in a parsimonious panel of pancreatic cancer survival markers.
The vaccine is delivered directly to patient lymph nodes early in cancer development, and used ctDNA clearance as a treatment response endpoint.
The NEMO assay detects aggressive neuroendocrine prostate cancer early in its evolution, potentially enabling treatment before resistance arises.
The TumorSight Viz application aims to make breast cancer treatment planning more precise through 3D tumor images built from standard-of-care medical imaging.
The company showed early data establishing a rheumatoid arthritis-specific expression signature and is enrolling patients into a larger study.
A study by researchers at Johns Hopkins and the Canadian Cancer Trials Group demonstrated that early molecular therapy response correlated well with radiographic findings.
The open-source CELLO2 algorithm helped identify a subset of glioma patients at high risk for developing resistance to Merck's Temodar (temozolomide).
The ambitious set of projects funded by BD² aims to improve our understanding of bipolar disorder and inform care across the entire spectrum of research and clinical practice.