Charlotte Hu
Articles Authored by Charlotte Hu
In heavily pretreated adults with Hodgkin's lymphoma, the therapy resulted in mostly grade 1 adverse events and no neurologic toxicities.
Turning Point's Repotrectinib Yields Promising Early Data in ROS1-, NTRK-Positive Cancers
The drugmaker has had discussion with the FDA about its regulatory plan for repotrectinib based on the efficacy and safety seen in interim analysis.
UCSF Glioblastoma Projects Using Molecular Data to Inform Subtypes, Match Patients to Treatments
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One project aims to collect patients' genomic and molecular information in a database, and another aims to tailor treatments based on patients' molecular profiles.
NRG1 gene fusions, found most commonly in lung and pancreatic cancer, are generating interest among drugmakers as a new precision medicine indication.
My Personal Therapeutics to Test Fruit Fly Avatar Technology in Gastrointestinal Cancer Patients
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The company, which uses fruit fly "avatars" to screen drugs, will be collaborating with London IVD Co-operative and Genomics England to test their technology in GI cancer patients.
Notable's Drug Sensitivity Assay IDs Rx for Blood Cancer Patients When NGS Can't, Small Study Shows
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Of the eight patients who received drugs recommended by the tumor board based on data from the drug sensitivity assay, 75 percent responded.
Lantern Pharma is using its RADR platform to repurpose two drugs currently in clinical trials and advance a new drug in preclinical testing.
BioNTech's Personalized Cancer Vaccine, Tecentriq Yield Few Responses but Promising Immune Activity
Investigators saw responses in one colorectal cancer and one breast cancer patient and are now studying differences between responders and non-responders.
Aprea's Drug for TP53-Mutant Cancers Moves Into Registrational Trials for Myelodysplastic Syndromes
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The drug, which is designed to restore normal functioning of p53, has allowed a promising proportion of TP53-mutated MDS patients to receive stem cell transplants in early trials.
Kinnate Exiting Stealth Mode With Plans to Move Lead RAF Inhibitor Into Clinical Trials Next Year
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The company raised $74.5 million in a series B financing round last December, with which it hopes to study its RAF inhibitor in various cancers with non-V600 BRAF mutations.