Catherine Shaffer

Articles Authored by Catherine Shaffer
The researchers hope to reproduce in a prospective clinical trial the model's 70 percent to 80 percent accuracy for predicting immunotherapy response.

The firm hopes to establish a role for cancer vaccines as a tumor shrinking therapy, not just a tumor preventing therapy.

The firm's lead candidate targeting DHX9 has shown preclinical activity in MSI-high cancers and is steadily progressing toward the clinic.
Blincyto sales continue to grow following positive data last year in acute lymphoblastic leukemia and an update to NCCN guidelines for pediatric patients.
Sales of Keytruda surged as the company advances the drug to earlier lines of therapy while looking ahead to combination therapy opportunities.
Tumor agnostic trials of Enhertu and two investigational ADCs suggest that targeting HER2 could be a successful strategy across a range of solid tumors.
Gene Expression Assay Shows Ability to Guide Targeted Treatment for Patients With Occult Cancers
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Patients with cancers of unknown primary had more treatment options and better outcomes when care was informed by a 90-gene expression assay.
UK Researchers Explore Digital Pathway for Facilitating Germline BRCA1/2 Testing
At ESMO, researchers described their experience using a streamlined pathway to facilitate pretest education and deliver test results to breast cancer patients.
Phase III Data at ESMO Support Rybrevant-Chemo as First-Line Therapy in Lung Cancer Subgroup
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Treatment-naïve NSCLC patients with EGFR exon 20 insertion mutations had better median progression-free survival on the regimen compared to chemo alone.
Studies Explore Activity of Neoadjuvant, Adjuvant Immunotherapy in HR-Positive Breast Cancer
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Patients who had Opdivo or Keytruda added to standard neoadjuvant and adjuvant therapy had significantly higher rates of pathologic complete response.