Microsatellite Instability Testing
The latest news on microsatellite instability testing.
Personalized Neoantigen Vaccine Shows Feasibility but Limited Efficacy in MSS Colorectal Cancer
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Researchers at AACR's annual meeting said they hope the vaccine will show stronger efficacy in patients with minimal residual disease.
A trial by MSK researchers has shown that neoadjuvant treatment with GSK's Jemperli spared 80 percent of patients with dMMR tumors from needing surgery.
NICE Recommends Opdivo, Yervoy in First-Line MSI-High, dMMR Colorectal Cancer
The decision is based on results from the Phase III CheckMate 8HW and the Phase II CheckMate 142 trials.
FDA Approves Opdivo, Yervoy as First-Line Treatment for MSI-High, dMMR Colorectal Cancer
The approval was based on results from a Phase III trial showing that Opdivo-Yervoy improved outcomes against Opdivo alone and chemo alone.
Early clinical results suggest the firm's antibodies targeting the Vβ T-cell receptor could induce strong and durable responses in cancer patients.