Immunotherapy
News and reporting on cancer immunotherapy.
'Fresh-In, Fresh Out' Dual-Targeted CAR T-Cell Therapy Shows Promise in Phase II DLBCL Trial
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The non-cryopreserved CD19- and CD20-directed CAR T-cell therapy zamto-cel is manufactured in a closed-system device that could enable point-of-care treatment.
Epsilogen Launches Phase Ib IgE Antibody Trial in Advanced Ovarian Cancer
In the study, the firm will enroll previously treated patients whose tumors are positive for FRα based on IHC testing.
Merck, Moderna Vax Trial Starts Enrolling Lung Cancer Patients at McGill University Health Center
The trials are evaluating an individualized neoantigen vaccine with Keytruda as an adjuvant therapy for non-small cell lung cancer.
Senti Biosciences Announces $37.6M PIPE Financing, Reports Early Data From Phase I CAR-NK Trial
The firm plans to put the proceeds toward further developing its cell therapy in CD33- or FLT3-expressing AML and for other R&D activities.
Despite Overall Survival Miss, Singapore Researchers Champion Success of Global Cell Therapy Trial
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The global Phase III VANCE trial of the autologous EBV-targeted T-cell therapy was the largest trial of a solid tumor cell therapy to date.