Drug Discovery & Development
News on drug screening, clinical trials, companion diagnostics, immunotherapy, & personalized therapies in genetics, genomics, and molecular diagnostics.
In a Phase I study presented at AACR's annual meeting, 71 percent of patients who hadn't received a prior anti-HER2 ADC responded to the drug.
BlackfinBio Launching Gene Therapy Trial in Rare Neurological Condition at Boston Children's
The UK-based company will evaluate BFB-101 in up to five children with hereditary spastic paraplegia type 47 in a Phase I/II trial.
A trial by MSK researchers has shown that neoadjuvant treatment with GSK's Jemperli spared 80 percent of patients with dMMR tumors from needing surgery.
Clasp Therapeutics Initiates Phase I Trial of T-Cell Engager
In the study, patients with advanced solid tumors must be HLA-A*02:01 positive and harbor a p53 R175H mutation.
Leukemia & Lymphoma Society Expands Pediatric AML Trial to Include Kura Oncology's Menin Inhibitor
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Leukemia patients who enroll in LLS's PedAL screening trial and are found to have certain alterations will be directed to receive ziftomenib in a Phase I study.